Three of the genome-wide significant loci have known associations with ND from our prior GWAS and others 6 : chr15q25 21,22,23 (smallest P = 1.6 10 39 for rs16969968, a well-established functional missense [D398N] CHRNA5 SNP 24 ) chr20q13 21 (smallest P = 1.2 10 12 for rs151176846, an intronic CHRNA4 SNP), and chr9q34 22 (smallest P = 1.1 10 8 for rs13284520, an intronic DBH SNP)
Then the system compares your DNA with others to determine the best mate that would allow you to fulfill your chosen traits
Benowitz, Pharmacology of Nicotine: Addiction, Smoking-Induced Disease, and Therapeutics, 2010
Les traits de stylo qui composent les lettres sont ceux de George Washington Hill
Marlboro is known for simple, strong, color-coded packaging